Insulin-like peptide

Details Insulin-like peptide Insulin-like peptide

1995-08-18

1997-09-23

Jagannathan, Vasu S.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Insulin; related peptides

530325, 530326, A61K 3828, C07K 1400

Patent

active

056706189

ABSTRACT:
A purified insulin-like protein (ILP) isolated from Saccharomyces cerevisiae is disclosed. The ILP has a molecular weight of approximately 6.4 kilodaltons and the amino acid sequence of the 22 amino terminal residues of the protein has been determined. Computer-assisted molecular graphics analysis of ILP illustrates the similarity of the sequenced portion to vertebrate insulin A-chains.

REFERENCES:
patent: 4548904 (1985-10-01), Kent et al.
Results of search of SWISSPROT database with ScILP amino acid sequences as queries 1994.
Results of search of GENEMDL database using nucleotide sequence of cloned PCR product as query 1994.
Description of BLASTN and BLASTP search programs 1994.
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