Insulin derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C530S303000

Reexamination Certificate

active

07615532

ABSTRACT:
The present invention relates to insulin derivatives which are naturally occurring insulins or analogues thereof which have a side chain attached either to the α-amino group of the N-terminal amino acid residue of the B chain or to the ε-amino group of a Lys residue present in the B chain of the parent insulin, the side chain being of the general formula:in-line-formulae description="In-line Formulae" end="lead"?-W-X—Y-Zin-line-formulae description="In-line Formulae" end="tail"?wherein W, X, Y and Z are as defined in the disclosure.

REFERENCES:
patent: 3528960 (1970-09-01), Haas
patent: 5898067 (1999-04-01), Balschmidt et al.
patent: 6251856 (2001-06-01), Markussen et al.
patent: 2002/0045731 (2002-04-01), Schaffer et al.
patent: 894095 (1997-02-01), None
patent: 0894095 (1999-02-01), None
patent: 1492997 (1976-07-01), None
patent: 91/12817 (1991-02-01), None
patent: 95/07931 (1994-09-01), None
patent: 98/02460 (1997-07-01), None

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