Chemistry: analytical and immunological testing – Clotting or clotting factor level tests
Patent
1985-11-19
1988-10-11
Marcus, Michael S.
Chemistry: analytical and immunological testing
Clotting or clotting factor level tests
436 45, 436165, 436177, 436909, 422 72, 422 73, G01N 2107, G01N 2147
Patent
active
047771410
ABSTRACT:
An instrument for measuring coagulation parameters is provided in which plasma and at least one reagent are mixed by spinning in a cuvette with transparent windows and in which measurement is then made of scatter by the mixture of the energy of a light beam sent into the mixture.
Upon spin, the plasma components and reagent are displaced into the chamber, thus determining the initiation of the presence of the mixture in which the clot forms, and a photodetecting unit senses the change in the energy of the scattered light, caused by clot formation.
REFERENCES:
patent: 4226531 (1980-10-01), Tiffany et al.
patent: 4252536 (1981-02-01), Kishimoto et al.
patent: 4373812 (1983-02-01), Stein et al.
patent: 4387992 (1983-06-01), Swartz
patent: 4558946 (1985-12-01), Galle et al.
C. D. Bertram et al, (Sep. 1984), "Optical Endpoint Sensing in an Automatic Whole Blood Clotting Timer", Med. & Biol. Eng. & Comput., vol. 22, pp. 401-405.
Calzi Claudio
Preda Luigi
Doernberg Alan M.
Fisher Scientific Company
Kummert Lynn M.
Marcus Michael S.
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