Instillation composition

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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Details

424256, A61K 31435, A61K 31415, A61K 3144

Patent

active

041917723

ABSTRACT:
An instillation composition, comprising an effective amount of at least one sparingly soluble active material suspended or partly dissolved in an aqueous emulsion containing a swelling agent. Advantageously the active substance is nitrofurantoin or a quinolone or pyridazine derivative, the active material has a particle size less than about 10 .mu.m and the swelling agent is a polysaccharide derivative present in about 0.3 to 3% by weight of the composition, the composition further containing at least one local anesthetic, antiphlogistic substance, emulsifier, buffer or stabilizer. With the invention, unit doses of only 50 ml. will contain sufficient active material.

REFERENCES:
patent: 1890860 (1932-12-01), Omohundro
patent: 3492399 (1970-01-01), Prigal
Goodman et al., "The Pharmacological Basis of Therapeutics", McMillan Co. (1955) p. 1118.

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