Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-03-18
1995-10-24
Chereskin, Che S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
435 691, A61K 3700, C12N 1585
Patent
active
054610320
ABSTRACT:
The invention provides insecticidally effective peptides isolatable from Diguetia spider venom, methods for preparing and using insecticides, and DNA encoding such insecticidally effective peptides.
REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4703008 (1987-10-01), Lin
patent: 4797279 (1989-01-01), Karamata et al.
patent: 4855405 (1989-08-01), Yoshioka et al.
patent: 4861595 (1989-08-01), Barnes et al.
patent: 4879236 (1989-11-01), Smith et al.
patent: 4918107 (1990-04-01), Nakajima et al.
patent: 4925664 (1990-05-01), Jackson et al.
Zlotkin et al., "An Excitatory and Depressant Insect Toxin from Scorpion Venom both Affect Sodium Conductance and Possess a Common Binding Site," Arch Biochem. Biophysics, 240:877-887, 1985.
Tomalski et al., "Insect paralysis by baculovirus-mediated expression of a mite neurotoxin gene," Nature, 352:82-85, 1991.
Stewart et al., "Construction of an improved baculovirus insecticide containing an insect-specific toxin gene," Nature, 352:85-88, 1991.
McCutchen et al., "Development of a Recombinant Baculovirus Expressing an Insect-Selective Neurotoxin: Potential for Pest Control," Biotechnology, 9:848-852, 1991.
Jackson et al., "Spider Toxins: Recent Applications in Neurobiology," Ann. Rev. Neurosci., 12:405-414, 1989.
Adams et al., Insect Neurochemistry and Neurophysiology, Borkovec et al., eds., Human Press: New Jersey, pp. 397-400, 1986.
Quistad et al., "Paralytic and Insecticidal Toxins from the Funnel Web Spider, Hololena curta," Toxicon, 29:329-336, 1991.
Bowers et al., "Identification and purification of an irreversible presynaptic neurotoxin from the venom of the spider Hololena curta," Proc. Natl. Acad. Sci. USA, 84:3506-3510, 1987.
Geren, "Neurotoxins and Necrotoxins of Spider Venoms," J. Toxicol.-Toxin Reviews, 5:161-170, 1986.
Grishin, "Toxic components from Buthus eupeus and Lycosa singoriensis venoms," Shemyakin Institute of Bioorganic Chemistry, U.S.S.R. Academy of Sciences, Moscow 117988, GSP-1, USSR.
Hermann et al., Methods in Enzymology, Academic Press, Inc., 152:180-183, 1987.
Jones et al., "Molecular Cloning Regulation and Complete Sequence of a Hemocyanin-Related Juvenile Hormone-Supressible Protein From Insect Hemolymphs," J. Biol. Chem., 265:8596, 1990.
Kaneda et al., "Scorpion toxin prolongs an inactivation phase of the voltage-dependent sodium current in rat isolated single hippocampal neurons," Brain Res.,487:192-195, 1989.
Blobel, "Intracellular Protein Topogenesis," Proc. Natl. Acad. Sci. USA, 77:1496-1500, 1980.
Sambrook et al., Molecular Cloning A Laboratory Manual, 2d Edition, Cold Spring Harbor Press, N.Y., 1989.
Fuqua et al., "A Simple Polymerase Chain Reaction Method for Detection and Cloning of Low-Abundance Transcripts," Biotechnique, 9:206-210, 1990.
Frohman, PCT Protocols, Innis et al., eds., Academic Press, Calif., pp. 28-38, 1990.
Raineri et al., "Agrobacterium-Mediated Transformation of Rice (Oryza Sativa L.)," Biotechnology, 8:33-38, 1990.
Fromm et al., "Inheritance and Expression of Chimeric Genes in the Progeny of Transgenic Maize Plants," Biotechnology, 8:833-839, 1990.
Carbonnell et al., "Synthesis of a gene coding for an insect-specific scorpion neurotoxin and attemps to express it using baculovirus vectors," Gene, 73:409-418, 1988.
Miller et al., "Bacterial, Viral, and Fungal Insecticides," Science, 219:715-721, 1983.
Chomczynski et al., "Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate-Phenol-Chloroform Extraction," Analytical Biochemistry, 162:156-159, 1987.
Saiki et al., "Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase," Science, 239:487-491, 1988.
McKnight et al., "Transcriptional Control Signals of an Eucaryotic Protein-Coding Gene," Science, 217:316, 1982.
Quicke et al., "Extended summaries Pesticides Group and Physicochemical and Biophysical Panel Symposium Novel Approaches in Agrochemical Research," Pestic. Sci., 20:315-317, 1987.
Dunwiddie, Electrophysiciological Techniques in Pharmacology, Alan R. Liss, Inc.: New York, pp. 65-90, 1986.
Summers et al., "A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedures," Texas Ag. Exp. Bull, 1555:1, 1988.
Luria et al., In General Virology, John Wiley and Sons: New York, Chapter 2, pp. 21-32, 1978.
Kuroda et al., "Synthesis of Biologically Active Influenza Virus Hemagglutinin in Insect Larvae," J. of Virology, 63:1677-1685, 1989.
Wood, "Protease Degradation of Autographa californica Nuclear Polyhedrosis Virus Proteins," Virology, 103:392:399, 1980.
Price et al., "Complementation of recombinant baculoviruses by coinfection with wild-type facilitates production in insect larvau of antigenic proteins of hepatitis B virus and influenza virus," Proc. Natl. Acad. Sci. U.S.A., 86:1453-1456, 1989.
Cutler, "Electroporation: Being Developed to Transform Crops," Ag. Biotech News, 7:3-4, 1990.
Vialard et al., "Synthesis of the Membrane Fusion and Hemagglutinin Proteins of Measles Virus, Using a Novel Baculovirus Vector Containing the .beta.-Galactosidase Gene," J. Virology, 64:3-50, 1990.
Rossi et al., "An Alternate Method for Synthesis of Double-stranded DNA Segments," J. Biol. Chem., 257:9226, 1982.
Stapleton et al., "Curtatoxins: Neurotoxic insecticidal polypeptides isolated form the funnel-web spider Hololena curta," J. Biol. Chem., 265:2054-2059, 1990.
Bentzien, "Biology of the Spider Diguetia imperiosa," The Pan-Pacific Entomologist, 49:110-123, 1973.
Hunter Jackson J. R.
Kral, Jr. Robert M.
Krapcho Karen J.
VanWagenen Bradford C.
Chereskin Che S.
FMC Corporation
NPS Pharmaceuticals Inc.
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