Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2008-07-01
2008-07-01
Hutson, Richard (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C536S023100, C435S320100, C435S252100
Reexamination Certificate
active
07393922
ABSTRACT:
The present invention relates generally to modifiedBacillus thuringiensis(Bt) insecticidal crystal proteins, also referred to as mutant toxins, with enhanced toxicity against a variety of insect genera, particularly mosquitos. The invention provides modified Bt Cry4Ba proteins, or mutant toxins, which have toxicity-enhancing sequence modifications at one or more positions within the amino acid sequence of the protein. The invention also provides polynucleotides encoding modified Cry4Ba proteins. The invention also provides insecticidal compositions comprising mutant toxins with a new or broadened insecticidal spectrum, and insecticidal compositions comprising polynucleotides encoding the modified Cry4Ba proteins.
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Abdullah Mohd Amir
Dean Donald H.
Calfee Halter & Griswold LLP
Hutson Richard
Kim Alexander D
The Ohio State University Research Foundation
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