Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Animal or plant cell
Patent
1999-01-12
2000-12-05
Schwartzman, Robert A.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Animal or plant cell
424405, 435 6, 4353201, 435468, 536 231, A01N 6300, C12Q 168, C12N 1563, C12N 1582, C07H 2104
Patent
active
061563099
ABSTRACT:
Insect viruses capable of killing at least one target insect pest quicker than previously described viruses and methods for conferring that phenotype of faster killing are provided. Further improvement in the speed of killing is obtained when the virus of this invention also contains a nonfunctional egt gene to reduce feeding by the infected larvae, inhibit growth and further mediate the earlier death of the infected insect and/or it also contains and expresses a DNA sequence encoding an insect-specific toxin. The faster killing phenotype is achieved by inactivating an ORF 603 of AcMNPV or an ORF 603 homolog of a different species of baculovirus. Improved insecticidal compositions and improved methods of controlling insects are also included within the scope of this invention.
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Black Bruce C.
Dierks Peter M.
Fleming Nancy C.
Miller Lois K.
American Cyanamid Corporation
Sandals William
Schwartzman Robert A.
University of Georgia Research Foundation
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