Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Reexamination Certificate
2006-02-13
2010-02-16
Saidha, Tekchand (Department: 1652)
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
C435S195000, C435S197000, C536S023200
Reexamination Certificate
active
07662372
ABSTRACT:
The present invention discloses DNA sequences encoding plant and novel lipid acyl hydrolase proteins having coleopteran specific insect inhibitory activity, as well as variants and permuteins having enhanced levels of activity directed to controlling coleopteran insect infestation and enhanced levels of expression in planta. Additionally, catalytic dyad active site conformation is disclosed for both dicot and monocot plant derived non-specific lipid acyl hydrolases having coleopteran insect inhibitory properties.
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Dessen et al., Crystal Structure of Human Cytosolic Phospholipase A2Reveals a Novel Topology and Catalytic Mechanism,Cell 97:349-360 (1999).
Alibhai Murtaza F.
Rydel Timothy J.
Ball Timothy K.
Monsanto Technology LLC
Saidha Tekchand
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