Inositol triphosphates

Details Inositol triphosphates Inositol triphosphates

1987-02-17

1989-07-25

Wiseman, Thomas G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

435155, 2524002, A61K 3166, C12P 702

Patent

active

048515604

ABSTRACT:
The disclosure of the present invention is directed to an inositol triphosphate compound, useful as a pharmaceutical agent, having the structural formula ##STR1## where (a) three of R.sub.1, R.sub.3, R.sub.5, R.sub.7, R.sub.10 and R.sub.11 are hydroxyl and the remaining three are phosphate and R.sub.2, R.sub.4, R.sub.6, R.sub.8, R.sub.9 and R.sub.12 are hydrogen;

REFERENCES:
patent: 2723938 (1955-11-01), Buckwalter et al.
patent: 3591665 (1971-07-01), Kimura et al.
P. E. Lim et al., Properties of Phytase Fractions F.sub.1 and F.sub.2 from Wheat Bran and the Myo-Inositol Phosphates Produced from Fraction F.sub.2, Biochimica et. Biophysica Acta, 302 (1973), 316-328.
Tomlinson et al, Biochemistry, vol. 1, No. 1, pp. 166-171 (Jan. 1962).
Kerr et al, Archives of Biochemistry and Biophysics, vol. 96, pp. 347-353 (1962).
Biochem. and Biophys. Res. Comm., vol. 120, No. 2, 481-485 (Apr. 30, 1984).
Nature, vol. 306, 67-69 (Nov. 1983).

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