Inositol phosphate analogues as calcium-antagonistic substances

Details Inositol phosphate analogues as calcium-antagonistic substances Inositol phosphate analogues as calcium-antagonistic substances

1992-06-24

1995-03-07

Dees, Jose G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514141, 554 74, 558155, 558156, 558161, A61K 3166

Patent

active

053958284

ABSTRACT:
A compound of the formula (I) ##STR1## in which R.sub.1 is e.g. phosphate,

REFERENCES:
patent: 4515722 (1985-05-01), Yang et al.
patent: 5157140 (1992-10-01), Siren
Barry V. L. Potter and Stefan R. Nahorski, "Synthesis and biology of inositol polyphosphate analogues." Biochemical Society Transactions, vol. 20, Jun. 1992.
C. E. Dreef et al., "Synthesis of Racemic 3-Methylphosphonate Analogues of Myo-Inositol 3,4-Bis-and 1,3,4-Trisphosphate," Tetrahedron, vol. 47, No. 26, Mar. 1991, pp. 4709-4722.
Copy of European Search Report dated Sep. 22, 1992.

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