Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-04-18
1996-08-06
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3144
Patent
active
055434185
ABSTRACT:
This invention relates to a technique for treating a mammal with rapamycin which comprises removal of blood from the patient, treatment of the formed blood elements with rapamycin which binds rapidly and reversibly with erythrocytes, and returning the treated blood cells to the circulatory system of the patient for the treatment of any of the diseases, syndromes, conditions, or immune responses which respond to treatment with rapamycin. Alternatively, blood to be treated with rapamycin can be obtained from a hematologically compatible donor mammal.
REFERENCES:
patent: 3929992 (1975-12-01), Sehgal
patent: 4401653 (1983-08-01), Eng
patent: 4885171 (1989-12-01), Surenda
patent: 4887995 (1989-12-01), Abraham
patent: 5078999 (1992-01-01), Warner
patent: 5100899 (1992-03-01), Caine
Abraham et al., Transplantation 52(1), 101-105 (1991).
Bowers et al., Transplantation 51(4) 847-50 (1991).
Lorenz et al., Agents and Actions 12(1/2), 64-80 (1982).
Cybulska et al., Japanese J. Pharmacology 55 (Supp. I), 202P, 0-412 (1991).
Kitao and Hattori, Cancer Research 40, 1351-1353 (1980).
Stepkowski and Kahan, Transplantation Proceedings 23(6), 3262-3264 (1991).
Chen et al., Transplantation Proceedings 23(4), 2239-2246 (1991).
Kay et al., Transplantation Proceedings, 23(6), 2760-2762 (1991).
Stepkowski et al., Transplantation 51(1), 22-26 (1991).
Martel et al., Can J. Physiol. Pharmacol. 33, 48-51 (1977).
Staruch et al., FASEB Journal 3(3), 3411 (1989).
DuMont et al., FASEB Journal 3(4) 5256 (1989).
Sehgal et al., J. Antibiotics 28(10), 727-32 (1975).
Baker et al., J. Antibiotics 31(6), 539-545 (1978).
Verzina et al., J. Antibiotics 28(10), 721-726 (1975).
Hoefnagels et al., The Lancet 901 (1988).
Dye and Walkins, British Medical Journal 1353, (1980).
Gruber et al., Pharmaceutical Research 6(7), 601-607 (1989).
Howrie et al.. Drug Intel. Clin. Pharm. 19 425-427 (1985).
O'Leary et al., Surg. Gyn. Ob. 154, 681-688 (1982).
Zincke and Woods, Surg. Gyn. Ob., 145, 183-188 (1977).
Alejandro et al., Diabetes 36, 269-273 (1987).
Bowen et al., Diabetes 29, (Supp. 1), 98-104 (1980).
Lagudzinski and Gorski, Folia Biologica (Praha)37, 21-26 (1991).
MacLeod, Immunology Letters 29, 123-125 (1991).
Gregory et al., J. Heart Lung Transplantation 11(1), pt. 2, 197 (1992).
Stepkowski et al., Transplantation Proceedings 23(1), 507-508 (1991).
Lemaire and Tillement, J. Pharm. Pharmacol. 34, 715-718 (1982).
Brom et al., Kidney International 21, 323-329 (1982).
Armstrong Jay J.
Sehgal Surendra N.
American Home Products Corporation
Boswell, Jr. R. F.
Goldberg Jerome D.
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