Injection-resistant materials and method of making same through

Details Injection-resistant materials and method of making same through Injection-resistant materials and method of making same through

1984-04-30

1986-01-07

Griffin, Ronald W.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Processes of preparing a desired or intentional composition...

424 27, 623 1, 8 9411, 128127, 1283355, 435 1, 523115, 604265, 604285, A61K 31625

Patent

active

045634858

ABSTRACT:
Infection-resistant materials, and methods of preparing same, suitable for use within the interior of a human or animal body in such forms as vascular grafts prostheses, or other implanted devices. The material is rendered infection-resistant by incorporating therein antimicrobial agents, such as nalidixic acid derivatives or metal salts of nalidixic acid derivatives. In particular illustrative embodiments, silver norfloxacin and silver pefloxacin, are complexed with natural or synthetic polymeric materials such as silk, polyester (e.g., Dacron), polyurethane, polytetrafluoroethylene, or silicone-based material, to provide long-term prevention of infections which may otherwise result during or after surgery or implantation of a device.

REFERENCES:
patent: 4049802 (1977-09-01), Fox
patent: 4271070 (1981-06-01), Miyata et al.
patent: 4353996 (1982-10-01), Marconi et al.
patent: 4401712 (1983-08-01), Morrison
patent: 4404197 (1983-09-01), Fox et al.
patent: 4446124 (1984-05-01), Fox et al.
patent: 4455146 (1984-06-01), Noda et al.
patent: 4462981 (1984-07-01), Smith
"Virulence of Pseudomonas Infection in Burned Rats and Mice", Fox, et al, Arch Surg., 101, pp. 508-512, Oct. 1970.
"Crystal Structure of 2-Sulfanilamidopyrimidinesilver(1)", Baenziger, et al, Inorganic Chemistry, 15, No. 8, pp. 1807-1809, (1976).
"Silver Treated Graft Materials for Coverage of Infected Burn Wounds", Fox et al, Ann. Chir. Plast.", 1979, 24, No. 3, pp. 265-267.
"Sulfadiazine Silver-Resistant Pseudomonas in Burns", Modak et al, Arch Surg, 116, 854-857, Jul. 1981.
"Antibiotic Bonding to Polytetrafluoroethylene with Tridodecylmethylammonium Chloride", Harvey et al, Surgery, Sep. 1982, pp. 504-512.
"Vascular Prosthetic Infection", Bennion et al, Infections in Surgery, Sep. 1982, pp. 45-55.
"Control of Burn Wound Infections by Pefloxacin and its Silver Derivative", Modak et al, Burns, 10, No. 3, pp. 170-178.
"Topical Therapy and the Development of Silver Sulfadiazine", Fox, Jr., Surgery, Gyn & Ob, 157, 82-88, Jul. 1983.

Affiliated with

Also associated with

Rating

Injection-resistant materials and method of making same through does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Injection-resistant materials and method of making same through , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Injection-resistant materials and method of making same through will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-112107