Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Pyrolysis product of a plant
Reexamination Certificate
2001-02-08
2009-10-20
Tate, Christopher R (Department: 1615)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
Pyrolysis product of a plant
C424S773000, C424S725000
Reexamination Certificate
active
07604822
ABSTRACT:
An anti-inflammatory injectable solution is prepared fromSymphytum officinaleroots by cutting and drying of the vegetal material; calcining it at a temperature of 550-600° C., over a period of 3 to 4 hours; dissolving the ash obtained in distilled water at a ratio of 1:100 to form a solution, the obtained solution is filtered under vacuum, followed by filtration through milipor or semper filters to produce a filtrate and the filtrate is subjected to boiling evaporation to produce a liquid having a viscosity of 6.57±0.5 cP; and then drying a thin layer of the liquid so producedat a temperature of 200-250° C., over a period of 5-15 minutes until a white powder is obtained; and thereafter dissolving said white powder in distilled water in amount of 1 to 700 mg to 100 ml distilled water or saline solution.
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patent: 2406790 (2005-04-01), None
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Petersen, G. et al. “Anti-inflammatory activity of a pyrrolizidine alkaloid-free extract of roots of Symphytum officiale in humans.”Planta Medica, 1993, vol. 59, No. 7, pp. A703-A704.
Database Biosis Online! Biosciences Information Services. Abstract of Petersen, G. et al. “Anti-inflammatory activity of a pyrrolizidine alkaloid-free extract of roots of Symphytum officinale in humans.” Database accession No. PREV199497204279 XP002183471.Planta Medica, (1993), vol. 59, No. 7, pp. A703-A704.
Commission of the European Community Brussels Oct. 26, 1992; Annex 2. Committee for proprietary Medicinal Products, “Herbal drugs with serious risks”.
Analysis, separation, and biossay of Pyrrolizidine alkaloids from comfrey (Symphytum officinale).
Imunomod Composition—Official analyses of the La Sapienza University of Rome, Vegetarian Biology Department.
Al-Awadi Danah
Imunomod S.R.L.
Ionascu Ofelia
Ladas and Parry LLP
Tate Christopher R
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