Injectable pharmaceutical composition

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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514169, 514178, 264 5, 264 13, A61K 914, A61K 3156

Patent

active

053606167

ABSTRACT:
Formulations of programmed-release medicinal products intended for parenteral administration by injection, comprising calibrated solid microspheres (1 to 300 microns) of active substances. Provided in this form, steroids (for example progesterone and 17-.beta.-estradiol) may constitute injectable contraceptives, and the action of drugs having an approximatively 24 hours lasting effect may be regulated and extended.

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patent: 5019400 (1991-05-01), Gombotz et al.
J. Garza Flores, et al., "Assessment of a New Low-Dose Once-A-Month Injectable Contraceptive," Contraception, vol. 35, No. 5, May (1988).
"Encyclopedia of Chemical Technology, Third Edition," vol. 15, John Wiley and Sons, pp. 470-493 (1981).
Institut national de la Propriete Industrielle, "Rapport de Recherche," (Search Report), Feb. 12, (1991).

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