Injectable opacifying composition containing liposomes of high e

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – X-ray contrast imaging agent

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424 9452, 424 9454, 424 945, A61K 4904

Patent

active

054458102

ABSTRACT:
Injectable aqueous composition intended for opacifying certain organs with a view to examination by X-rays. This composition is based on liposomes containing, encapsulated thereein, an aqueous solution of an iodinated opacifying agent. The ratio between the weight of iodine encapsulated by the liposomes and the weight of the lipids from which their membrane is formed is not lower than 1.5 mg/mg.

REFERENCES:
patent: 4192859 (1980-03-01), Mackaness et al.
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4241046 (1980-12-01), Papahadjopoulos et al.
patent: 4529561 (1985-07-01), Hunt et al.
patent: 4567034 (1986-01-01), Charles et al.
patent: 4599227 (1986-08-01), Dees et al.
patent: 4647447 (1987-03-01), Gries et al.
patent: 4744989 (1988-05-01), Payne et al.
Liposome Dialysis for Improved Size Distribution, Bosworth et al., Journal of Pharmaceutical Scences, vol. 71, No. 7, Jul. 1982, pp. 806-812.
Liposome Filtration, Dependence on Transition Temperature, Brendzel et al., Biochima et Biophysica Acta 596 (1980), pp. 129-136.
Materials Properties of Liposomal Bilayers, Gruner, Princeton University, Princeton, N.J. (1987).
Preparation of Liposomes of Defined Size Distribution By Extrusion Through Polycarbonate Membranes, Olson et al., Biochimica et Biophysica Acta 557 (1979), pp. 9-23.
Size and Permeability of Liposomes Extruded Through Polycarbonate Membranes, Morii et al., International Journal of Pharmaceutics, (1983), pp. 215-224.
Preparation of Unilamellar Liposomes of Intermediate Size (0.1-0.2 .mu.m) by a Combination of Reverse Phase, Szoka, Evaporation and Extrusion Through Polycarbonate Membranes, Biochimica et Biophysica Acta, 601 (1980), pp. 559-571.
Liposome Disposition In Vivo, Abra et al., Biochimica et Biophysica Acta, 666 (1981) pp. 493-503.
Procedures for Preparation of Liposomes with Large Internal Aqueous Space and High Capture by Reverse-Phase Evaporation, Szoka et al. (1978), pp. 4194-4198.
"Procedure for preparation of liposomes with large internal aqueous space and high capture by reerse-phase evaporation", Szoka, et al., Proc. Natl. Acad. Sci. USA, vol. 75, No. 9, pp. 4194-4198, Sep. 1978.
"Radiopaque Liposomes for Imaging of the Spleen and Liver", Rozenberg, vol. 149, No. 3, Dec. 1983.
Chemical Abstracts (106:125855W) 1987.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Injectable opacifying composition containing liposomes of high e does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Injectable opacifying composition containing liposomes of high e, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Injectable opacifying composition containing liposomes of high e will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1818263

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.