Injectable, long-acting microparticle formulation for the delive

Details Injectable, long-acting microparticle formulation for the delive Injectable, long-acting microparticle formulation for the delive

1982-07-29

1985-07-23

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514180, A61K 3158

Patent

active

045308403

ABSTRACT:
An anti-inflammatory agent containing microparticle composition prepared by a process, comprising (a) dissolving or dispersing an anti-inflammatory agent in a solvent and dissolving a biocompatible and biodegradable wall forming material in said solvent; (b) dispersing said solvent containing said anti-inflammatory agent and wall forming material in a continuous phase processing medium; (c) evaporating a portion of said solvent from said dispersion of step (b), thereby forming microparticles containing said anti-inflammatory agent in the suspension; and (d) extracting the remainder of the solvent from said microcapsules.

REFERENCES:
patent: 4066747 (1978-01-01), Capozza
patent: 4196188 (1980-04-01), Besins et al.
patent: 4267173 (1981-05-01), Draper et al.
patent: 4328204 (1982-05-01), Wasserman et al.
patent: 4374121 (1983-02-01), Cioca
patent: 4389330 (1983-06-01), Tice et al.

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