Injectable gamma globulin

Details Injectable gamma globulin Injectable gamma globulin

1978-04-27

1979-08-21

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Lymphokine

260112B, 424177, 424 86, 424 87, A61K 3900, A61K 3942, A61K 3700, C07G 700

Patent

active

041653700

ABSTRACT:
A process is provided for the preparation of a gamma globulin suitable for intravenous administration from the readily available Fraction II or II + III plasma protein paste. The Fraction II or II + III paste is extracted with water at a pH of 4.8-6.5 and impurities are fractionally precipitated by addition of polyethylene glycol to 4% of wt./vol. and then 5% wt./vol. The desired gamma globulin is then precipitated at a pH 8.0 by addition of polyethylene glycol to 12% wt./vol.

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