Injectable formulations of 7-[D-.alpha.-amino-.alpha.-(p-hydroxy

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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A61K 3154

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active

040014096

ABSTRACT:
Antibacterial compositions comprising 7-[D-.alpha.-amino-.alpha.-(p-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5- ylthiomethyl)-3-cephem-4-carboxylic acid in the form of a hydrate or a hydrochloride salt and a sodium, potassium or calcium salt of levulinic acid have been found to be stable, useful, water-soluble forms of the cephalosporin antibiotic especially advantageous for parenteral administration.

REFERENCES:
patent: 3855213 (1974-12-01), Dunn et al.
patent: 3867380 (1975-02-01), Dunn et al.
Proskouriakoff, Jacs., vol. 55, pp. 2132-2134, (1933).

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