Injectable fomulations of disulfiram for the treatment of alcoho

Details Injectable fomulations of disulfiram for the treatment of alcoho Injectable fomulations of disulfiram for the treatment of alcoho

1985-02-01

1987-07-07

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

424 78, 424486, A61K 3116, A61K 922, A61K 930, A61K 932

Patent

active

046788093

ABSTRACT:
The disclosure is of the use of an injectable formulation of disulfiram for the treatment of alcoholism. One formulation comprises disulfiram and a biodegradable polymer. Another formulation comprises a slurry of disulfiram in normal saline. After injection, disulfiram is released from the injection site in a sustained-release manner.

REFERENCES:
Bergstrom et al Lancet, 1: 49-50, 1982.
Chem Abst., 86: 127,227k 1977.
Chem Abst., 91: 62662e, 1979.
Chem Abst. 92: 203,452w 1980.
Chem Abst., 92: 105587z, 1980.
Chem. Absts., 102: 172533s, 1985.

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