Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-08-21
1994-10-04
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 2, 514 21, 530399, A61K 3736, A61K 3718, A61K 910, A61K 3700
Patent
active
053526627
ABSTRACT:
Described is a preferred injectable, extended release formulation which includes a growth hormone or a growth hormone releasing factor in a carrier including a biocompatible hydrophobic vehicle and an amount of polyglycerol ester effective to extend release of the growth hormone or growth hormone releasing factor in an animal. Other preferred embodiments provide methods for making a composition for treating an animal with a growth hormone or growth hormone releasing factor, and methods for administering these substances to an animal.
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patent: 4977140 (1990-12-01), Ferguson et al.
patent: 5013713 (1991-05-01), Mitchell
Hawley's Condensed Chemical Dictionary, 11th Ed., p. 567.
"Monograph French Pharmacopeia" 10th Edition, 1990, entries on Polyglycolized Glycerides and Saturated Polyglycolized Glycerides, including translations by Gattefosse Corporation.
Brown et al., "Chemical Synthesis and Cloning of a Tyrosine tRNA Gene", Methods in Enzymology, vol. 68, pp. 109-151 (1979).
Baichwal, M. R. et al., "Sustained Release Capsules Using Polyglycerol Esters", The Indian Journal of Pharmacy, vol. 35, No. 4, pp. 146-150 (1973).
Labhasetwar, P. K. et al., "Study of Shellac Glycerol Esters as Microencapsulating Materials", J. Microencapsulation, vol. 6, No. 1, pp. 115-118 (1989).
Starha, L., et al., "Higher Fatty Acids and Their Glycerol Esters in per os Administered Medicines with Protracted Action", Acta Facultatis Pharmaceuticae Universitatis Comenianea, vol. 21, pp. 193-194 (1972).
Babayan, V. K., "Polyfunctional Polyglycerols and Their Esters", Food Product Development, Apr.-May (1968).
Brooks Norman D.
Needham Gregory F.
Schain Howard E.
Touzeau Phynn
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