Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1995-05-09
1997-04-15
Hulina, Amy
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424422, 424426, 523105, 523113, A61K 600
Patent
active
056207000
ABSTRACT:
The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days.
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Berggren Randall G.
Enscore David J.
Marks Susan M.
Osborne James L.
Roorda Wouter E.
ALZA Corporation
Dillahunty Mary Ann
Hulina Amy
Stone Steven F.
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