Injectable contraceptive vaccine and method

Details Injectable contraceptive vaccine and method Injectable contraceptive vaccine and method

1978-02-23

1978-10-31

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

424 85, 424100, 424105, 424177, 424238, 424243, A61K 3900

Patent

active

041235193

ABSTRACT:
An injectable contraceptive vaccine, a method of preparing said vaccine and the method of preventing conception in mammals by use of said vaccine, is disclosed. A vaccine which stimulates the production of antibodies directed against a hormone essential to the reproductive cycle of a mammal is prepared by coupling such a hormone to a carrier to form a hormone-carrier conjugate. Conception in mammals is prevented by injection of such vaccine during the proper period of the reproductive cycle of said mammal.
Specifically described is the vaccine prepared by coupling a hormone, such as estradiol-17 beta, with a protein and its use to sterilize a female of the canine species.

REFERENCES:
CA.84 No. 159864r, No. 159865s (1976).
CA.83 No. 191210q, No. 188650c, No. 129524s (1975.
CA.80 No. 23006x, No. 106544x (1974).
CA.79 No. 64420a (1973).
CA.77 No. 56941q (1972).
CA.84 No. 40423f, No. 40425h (1976).
CA.82 No. 122178c, No. 122179d, No. 151517t, No. 151518u, No. 15159v (1975).
CA.81 No. 48386e (1974).
CA.79 No. 51604p, No. 64068s, No. 16679v, No. 112892e (1973).
CA.77 No. 101991u, No. 31179j, No. 147777g, No. 147778h (1972).
CA.76 No. 97742y, No. 138870j (1972).

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