Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1978-02-23
1978-10-24
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Lymphokine
424 85, 424100, 424105, 424177, 424238, A61K 3724, A61K 3900
Patent
active
041221664
ABSTRACT:
An injectable contraceptive antiserum, a process of preparing said antiserum and the method of preventing conception in mammals by the use of said antiserum, is disclosed. An antigen which causes the production of antibodies directed against a hormone essential to the reproductive cycle of mammal is prepared by coupling such a hormone with a carrier to form a hormone-carrier conjugate. A mammal is injected with said conjugate, and the produced antiserum is recovered from blood obtained from said mammal. Conception in mammals is prevented by injection of such recovered antiserum during the proper period of the reproductive cycle of said mammal.
Specifically described is the antiserum recovered from the blood of a mammal which has been injected with an antigen prepared by coupling a hormone, such as, estradiol-17 beta with a protein and its use to temporarily sterilize a female of the canine species.
REFERENCES:
C.A.84, #159864r, #159865s (1976).
C.A.83, #191210q, #188650c, #129524s (1975).
C.A.80, #23006x, #106544x (1974).
C.A.79, #64420a (1973).
C.A.77, #56941q (1972).
C.A.84, #40423f, #40425h (1976).
C.A.82, #122178c, #122179d, #151517t, #151518u, #151519v (1975).
C.A.81, #48386e (1974).
C.A.79, #51604p, #64068s, #16679v, #112892e (1973).
C.A.77, #101991u.
C.A.77, #31179j, #147777g, #147778h (1972).
C.A.76, #97742y, #138870j (1972).
Stagg Charles M.
Tribble Ronald L.
Philips Roxane, Inc.
Rose Shep K.
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