Injectable compositions of amoxycillin trihydrate

Details Injectable compositions of amoxycillin trihydrate Injectable compositions of amoxycillin trihydrate

1987-09-17

1989-10-24

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Lymphokine

514197, H61K 3179, H61K 3143

Patent

active

048760862

ABSTRACT:
Injectable pharmaceutical compositions are provided which comprise fine particles of amoxycillin trihydrate coated with a dispersing agent, the ratio of amoxycillin trihydrate to dispersing agent being from 1000:1 to 20:1. A preferred dispersing agent is a mixture of polyvinylpyrrolidone and lecithin. Such compositions give surprising prolonged blood levels of amoxycillin after administration. The compositions can be used in the treatment of both humans and domestic animals.

REFERENCES:
patent: 2897120 (1959-07-01), Cronin et al.
patent: 2939818 (1960-06-01), Berger
patent: 3062718 (1969-11-01), Spiegel
patent: 3674776 (1972-07-01), Long et al.
patent: 3969524 (1976-07-01), Emodi et al.
patent: 4423033 (1983-12-01), Taskis
The Theory & Practice of Industrial Pharmacy, pp. 108-110 (1976).

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