Injectable compositions of a cephalosporin dihydrate salt

Details Injectable compositions of a cephalosporin dihydrate salt Injectable compositions of a cephalosporin dihydrate salt

1994-02-18

1995-03-28

Rizzo, Nicholas

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514202, C07D50146, A61K 31545

Patent

active

054018420

ABSTRACT:
The present invention provides physical admixtures of a new crystalline dihydrochloride dihydrate salt of the cephalosporin antibiotic, cefepime with a pharmaceutically acceptable non-toxic organic or inorganic base. In particular, this invention provides physical admixtures having a temperature and moisture stable crystalline dihydrochloride dihydrate form of cefepime having a specific X-ray powder diffraction pattern as described herein.

REFERENCES:
patent: 4406899 (1983-09-01), Aburaki et al.
patent: 4910301 (1990-03-01), Kaplan et al.
patent: 4994451 (1991-02-01), Kaplan et al.

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