Injectable aqueous solution containing hydrogensulfite and/or su

Details Injectable aqueous solution containing hydrogensulfite and/or su Injectable aqueous solution containing hydrogensulfite and/or su

1984-02-15

1987-10-20

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds bacterium or component thereof or substance produced...

514220, A61K 3304, A61K 3155

Patent

active

047013257

ABSTRACT:
An alkali metal hydrogensulfite or sulfite is effective for controlling a local injury such as inflammation and vein injury occurring on the injection of an antitumor benzodiazepine compound of the formula ##STR1## wherein R.sub.1 denotes hydrogen atom, or acyl, carbamyl, or alkoxycarbonyl group; R.sub.2 denotes hydrogen atom or acyl group; and R.sub.3 denotes sulfinic acid rest, SO.sub.2 X, or sulfonic acid rest, SO.sub.3 X, X meaning hydrogen, alkali metal or alkaline earth metal. An aqueous solution containing the both can be administered by injection.

REFERENCES:
patent: 4309437 (1982-01-01), Ueda et al.
Dyer, An Index of Tumor Chemotherapy, 1949, WIH, p. 37.

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