Initial screen for abnormal platelet condition

Details Initial screen for abnormal platelet condition Initial screen for abnormal platelet condition

1995-02-16

1996-10-29

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving blood clotting factor

436 69, F41A 3300, G01N 3366

Patent

active

055695906

ABSTRACT:
Described is a novel screening method for detecting an abnormal platelet condition in blood, and a kit for use in such a method. An initial screen for an abnormal platelet condition in blood applies to a non-interfering test surface a platelet rich plasma specimen from the blood and an aqueous reagent including a hydroxy-substituted aromatic compound (preferrably propyl gallate) and a metal ion, (such as Ni.sup.2+, Co.sup.2+, or Cu.sup.2+) in concentrations sufficient to cause platelet aggregation in a normal platelet rich plasma sample upon agitation, lightly agitating the platelet rich plasma specimen in contact with the reagent, and visually detecting for the presence of platelet aggregates in the specimen.

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