Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-07-31
2007-07-31
Schultz, J. Douglas (Department: 1635)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100, C536S024100, C536S024300, C435S006120, C435S091100, C435S325000, C514S04400A
Reexamination Certificate
active
10317250
ABSTRACT:
There are disclosed novel polypeptides referred to as Pellino polypeptides, as well as fragments thereof, including immunogenic peptides. DNAs encoding such polypeptides as well as methods of using such DNAs and polypeptides are also disclosed.
REFERENCES:
patent: 6013787 (2000-01-01), Monia et al.
patent: 6649411 (2003-11-01), Gozes et al.
patent: 6703487 (2004-03-01), Bird et al.
patent: 6770633 (2004-08-01), Robbins et al.
patent: 2002/0150934 (2002-10-01), Powers et al.
patent: 2004/0005615 (2004-01-01), Li et al.
patent: 2004/0034199 (2004-02-01), Bird et al.
patent: 1 074 617 (2001-02-01), None
patent: WO 00/58350 (2000-10-01), None
patent: WO 01/09318 (2001-02-01), None
patent: WO 01/83739 (2001-11-01), None
patent: WO 02/21138 (2002-03-01), None
patent: WO 03/059611 (2002-08-01), None
patent: WO 03/100000 (2003-12-01), None
Rich, T. et al., “Pellino-related sequences fromCaenorhabditis elegansandHomo sapines”, Immunogenetics51(1-2): 145-149; Nov. 2000.
Ota, T. et al., “Human protein sequence SEQ ID No. 15204”, GeneSeq Database Accession No. AAB94502; Jun. 26, 2001.
Rosen, C. A. et al., “Human secreted protein BLAST search protein SEQ ID No. 172”, GeneSeq Database Accession No. AAB32114; Feb. 14, 2001.
Rich, T. et al. (Reference 1) and Rich, T. (Reference 2), “Pellino [Homo sapiens]”, NCBI Protein/GenBank Database Accession No. CAC04320; Aug. 23, 2000.
Kennedy, E.J. and Moynagh, P.N. (References 1 and 2), “Homo sapienspellino related intracellular signalling molecule (PRISM) mRNA, complete cds”, NCBI Nucleotide/GenBank Database Accession No. AF300987; Oct. 1, 2000.
Resch, K. et al., “pellino (Drosophila) homolog 2 [Homo sapiens]”, NCBI Protein/GenBank Database Accession No. NP 067078; Nov. 2, 2000.
NCBI Annotation Project, “pellino (Drosophila) homolog 2 [Homo sapiens]”, NCBI Protein/GenBank Database Accession No. XP—007338; Feb. 10, 2001.
Rich, T. et al. (Reference 1) and Rich, T. (Reference 2), “Homo sapiensmRNA for Pellino protein (ORF1)”, NCBI Nucleotide/GenBank Database Accession No. AJ278859, Mar. 11, 2001.
Resch, K. et al. (References 1 and 2), “pellino 1 [Homo sapiens]”, NCBI Protein/GenBank Database Accession No. AF302505 1, now Accession No. AAG15393; Sep. 21, 2000.
Grosshans, J. et al., “Oligomerisation of Tube and Pelle leads to nuclear localisation of Dorsal”,Mechanisms of Development81(1-2): 127-138; Mar. 1999.
Rich, T. et al., “How low can Toll go?”,Trends in Genetics16(7): 292-294; Jul. 2000.
Kennedy, E.J. and Moynagh, P.N., “PRISM, a novel mediator of Toll/IL-1 signalling”,FASEB J. 15(4): A209; Mar. 7, 2001.
Resch, K. et al., “Assignment of homologous genes, Peli1/PELI1 and Peli2/PELI2, for the Pelle adaptor protein Pellino to mouse chromosomes 11 and 14 and human chromosomes 2p13.3 and 14q21, respectively, by physical and radiation mapping”,Cytogenetics and Cell Genetics92(1-2): 172-174; 2001.
Grosshans, J. (Reference 1), Grosshans, J. et al. (Reference 2), and Grosshans, J. and Nusslein-Volhard, C. (Reference 3), EMBL Database Accession No. AF091624, Sep. 28, 1998.
Yu, K.-Y. et al., “Cutting Edge: Mouse Pellino-2 Modulates IL-1 and Lipopolysaccharide Signaling”,Journal of Immunology169(8): 4075-4078, Oct. 15, 2002.
Jiang, Z. et al., “Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex,”J. Biol. Chem., 278(13):10952-10956, 2003.
Li, S. et al., “IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase,”Proc. Natl. Acad. Sci. U.S.A., 99(8):5567-5572, 2002.
Wells J.A., “Additivity of mutational effects in proteins,”Biochemistry29:8509-8517, 1990.
Ngo J.T. et al., “Computational complexity, protein structure prediction, and the levinthal paradox,” In: The Protein Folding Problem and Tertiary Structure Prediction, Merz and Le Grand, Eds., Birkhauser, Boston pp. 491-495, 1994.
Bird Timothy A.
Cosman David J.
Li Xiaoxia
Chong Kimberly
Immunex Corporation
Perkins Patricia Anne
Schultz J. Douglas
Sprunger Suzanne
LandOfFree
Inhibitory Pellino nucleic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Inhibitory Pellino nucleic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitory Pellino nucleic acids will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3751102