Inhibitors of β-lactamase

Details Inhibitors of β-lactamase Inhibitors of β-lactamase

2007-08-21

2007-08-21

Davis, Zinna N. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S342000, C514S397000, C514S438000, C514S448000, C546S153000, C546S280400, C548S315100, C549S070000, C549S075000, C549S078000

Reexamination Certificate

active

10884435

ABSTRACT:
The intention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel β-lactamase inhibitors, which are structurally unrelated to the natural product and semi-synthetic β-lactamase inhibitors presently available, and which do not require a β-lactam pharmacophore. The invention also provides pharmaceutical compositions and methods for inhibiting bacterial growth.

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