Inhibitors of the GPIb—vWF interaction, their...

Details Inhibitors of the GPIb—vWF interaction, their... Inhibitors of the GPIb—vWF interaction, their...

2007-06-26

2007-06-26

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S313000, C514S339000, C514S367000, C514S394000, C544S405000, C546S159000, C546S268100, C548S159000, C548S304700

Reexamination Certificate

active

10454939

ABSTRACT:
The present invention relates to compounds of the formula I, in which R1, R2, A, B, D, F, n, m and o have the meanings indicated herein. The compounds of the formula I are valuable pharmacologically active compounds. They are reversible inhibitors of the interaction between the plasma protein von Willebrand factor (vWF) and the blood platelet receptor glycoprotein Ib-IX-V complex (GPIb). They exhibit an antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of atherothrombotic diseases

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