Inhibitors of the conversion of big endothelin to endothelin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Patent

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Details

514 16, 514 19, 530328, 530329, A61K 3800, C07K 506, C07K 706, C07K 700

Patent

active

055040705

ABSTRACT:
Novel and known compounds are described which inhibit endothelin converting enzyme (ECE), thereby preventing the conversion of Big Endothelin (BET) to Endothelin (ET). Pharmaceutical usefulness and preparations are described.

REFERENCES:
patent: 4452790 (1984-06-01), Karanewsky
patent: 4610816 (1986-09-01), Berger
patent: 4918105 (1990-04-01), Cartwright

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Profile ID: LFUS-PAI-O-2016366

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