Inhibitors of the 11-β-hydroxysteroid dehydrogenase...

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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RE041135

ABSTRACT:
The present invention relates to compounds that are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.

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