Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2003-12-19
2009-02-03
McKane, Joseph K. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S541000
Reexamination Certificate
active
07485664
ABSTRACT:
The present invention relates to compounds that inhibit TACE, compositions thereof, and methods of using those compounds and compositions for treating diseases.
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Levin et al., Acetylenic TACE Inhibitors, Bio. & Med. Chem. Lett., vol. 13 (2003), pp. 2799-2803, especially p. 2799.
Levin et al., “Acetylenic TACE Inhibitors Part 1. SAR of the Acyclic Sulfonamide Hydroxamates”, Bioorganic Medicinal Chemistry Letters, vol. 13, No. 16, pp. 2799-2803, 2003.
Sum et al., “Cyclic Amine Sulfonamides as Linkers in the Design and Synthesis of Novel Human β3Adrenergic Receptor Agonists”, Bioorganic Medicinal Chemistry Letters, vol. 13, No. 13, pp. 2191-2194, 2003.
Bandarage Upul
Bhisetti Govinda Rao
Come Jon H.
Perola Emanuele
Saunders Jeffrey O.
Badia Michael C.
Chung Susannah
McKane Joseph K.
Vertex Pharmaceuticals Incorporated
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