Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-04-29
1998-07-21
Russel, Jeffrey E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 18, 514 19, 514533, 514542, 514557, 514559, 514561, 514562, 514563, 514572, 514613, 514616, 514617, 514619, 514621, 514729, 530330, 530331, 548251, 548253, 548254, 560 19, 560 37, 560 45, 560 48, 560 49, 560 76, 560123, 562405, 562426, 562433, 562442, 562443, 562452, 562465, 562480, 562488, 562489, 562505, 562553, 562607, 564 57, 564152, 564153, 564155, 564161, 564163, 564164, 564169, 564180, A61K 3116, A61K 3119, A61K 31215, A61K 3141
Patent
active
057835934
ABSTRACT:
The present invention provides a compound of the formula ##STR1## which inhibit squalene synthetase and cholesterol biosynthesis and are useful in the treatment of e.g., hyperlipidaemia, atherosclerosis, or fungal infections, processes for the preparation of the compounds of the invention, intermediates useful in these processes, and pharmaceutical compositions containing the compounds.
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Baker William R.
Donner B. Gregory
Fakhoury Stephen A.
Fung Anthony K. L.
Garvey David S.
Abbott Laboratories
Crowley Steven R.
Russel Jeffrey E.
Steele Gregory W.
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