Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-07-10
2000-02-08
Moezie, F. T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514318, 514330, 514 12, A61K 31445, A61K 3818
Patent
active
060228784
ABSTRACT:
This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
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Dawson Ted
Hamilton Gregory S.
Snyder Solomon
Steiner Joseph P.
GPI Nil Holdings Inc.
John Hopkins University School of Medicine
Juneau Todd L.
Moezie F. T.
Nath Gary M.
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