Inhibitors of rotamase enzyme activity

Details Inhibitors of rotamase enzyme activity Inhibitors of rotamase enzyme activity

1995-06-07

1998-08-25

Jarvis, William R. A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514293, 514300, 514302, 514248, 514326, 514330, A61K 3150, A61K 3144, A61K 31445

Patent

active

057983550

ABSTRACT:
This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.

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