Inhibitors of retroviral proteases

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

562 16, C07D20904, C07F 928

Patent

active

056294310

ABSTRACT:
The present invention relates to compounds of the formula I ##STR1## in which A, Q, R.sup.2, R.sup.3, R.sup.4 and the corresponding radicals with an * are defined as indicated in the description, a process for the preparation thereof, and the use thereof for inhibiting retroviral proteases.

REFERENCES:
patent: 3359266 (1967-12-01), Maier et al.
patent: 4100275 (1978-07-01), Ratcliffe et al.
Maier, et al., Phosphorous Sulfur, 8(1) 67-71 1980.
Jasny, et al., Science 260 1253-93 1993.
Talal, et al., Immunology Today, 4(7) 180-85 1983.
Habeshaw, et al., Immunology Today, 13(6) 207-10 1992.
Phosphous Sulfur (1980),8(1), 67-71 [Chem. Abstract 93:132560n].
Jasny, et al., "AIDS The Unanswered Questions", Science 260, (1993), 1253-1293.
Talal, et al., "A Clinician and a Scientist Look at Aquired Immune-Deficiency Syndrome (AIDS)", Immunology Today, 4(7), (1983), 180-185.
Habeshaw, et al., "Does the HIV Envolope Induce a Chronic Graft-Virus-Host-Like Disease?", Immunology Today, 13(6), (1992), 207-10.
Maier, Phosphorus and Sulfur, vol. 14, pp. 295-322 (1983).
Bartlett et al., Journal of American Chemical Society, vol. 106, pp. 4282-4283 (1984).
Katoh et al., Nature, vol. 329, pp. 654-656 (Oct. 15, 1987).
Billich et al., The J. of Biological Chem., vol. 263, No. 34, pp. 17905-17908 (Dec. 5, 1988).
Moore et al., Biochemical and Biophysical Res. Communications, vol. 159, No. 2, pp. 420-425 (Mar. 15, 1989).
Richards et al., FEBS Letters vol. 247, No. 1, pp. 113-117 (Apr. 1989).
von der Helm et al., FEBS Letters, vol. 247, No. 2, pp. 349-352 (Apr. 1989).
Meindl et al., Chemical Abstracts, vol. 78, 30152d, p. 540 (1973).
Rehse et al., Chemical Abstracts, vol. 108, 74899v, p. 633 (1988).
Pechik et al., FEBS Letters, vol. 247, No. 1, pp. 118-122 (Apr. 1989).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Inhibitors of retroviral proteases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inhibitors of retroviral proteases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitors of retroviral proteases will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1386685

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.