Inhibitors of retroviral protease

Details Inhibitors of retroviral protease Inhibitors of retroviral protease

1994-01-07

2000-09-19

Woodward, Michael P.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

6 to 7 amino acid residues in defined sequence

530334, 530338, 514 16, 514 17, C07K 702, A61K 3808

Patent

active

061214175

ABSTRACT:
Novel inhibitors of retroviral protease, e.g., HIV protease, are provided which are peptides having from about 4 to about 8 amino acid residues and which are substrates for said protease derived from known cleavage sites and modified to contain an internal CH.sub.2 NH bond isostere.

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