Inhibitors of retroviral protease

Details Inhibitors of retroviral protease Inhibitors of retroviral protease

1989-03-08

1994-08-30

Cashion, Jr., Merrell C.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

6 to 7 amino acid residues in defined sequence

C07K 706, A61K 3702

Patent

active

053429222

ABSTRACT:
Novel inhibitors of retroviral protease, e.g., HIV protease, are provided which are peptides having from about 4 to about 8 amino acid residues and which are substrates for said protease derived from known cleavage sites and modified to contain an internal CH.sub.2 NH bond isostere.

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