Inhibitors of proteasomal activity for stimulating bone growth

Details Inhibitors of proteasomal activity for stimulating bone growth Inhibitors of proteasomal activity for stimulating bone growth

2005-06-07

2005-06-07

Gitomer, Ralph (Department: 1651)

Drug, bio-affecting and body treating compositions

Dentifrices

C424S093200, C435S029000

Reexamination Certificate

active

06902721

ABSTRACT:
The present invention relates to compounds that inhibit the activity of the proteasome or the production of proteasomal proteins and promote bone formation and are thus useful in treating osteoporosis, bone fracture or deficiency, primary or secondary hyperparathyroidism, periodontal disease or defect, metastatic bone disease, osteolytic bone disease, post-plastic surgery, post-prosthetic joint surgery, and post-dental implantation, in subject where this is desirable.

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