Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1994-10-26
1996-11-12
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514114, 514119, 514125, 514134, 558155, 558166, 558170, 558177, 558178, 558184, 558189, 558217, 562 8, 562 11, 562 15, 562 16, 562 20, 562 21, 562 22, A61K 3166, C07F 940, C07F 938, C07F 924
Patent
active
055740251
ABSTRACT:
The compounds disclosed inhibit the prenylation of several proteins. These compounds are potent inhibitors of famesyl-protein transferase and geranylgeranyl-protein transferase. Further contained in this invention are chemotherapeutic compositions containing these prenyl-transferase inhibitors and methods for their production.
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Anthony Neville J.
Gomez Robert P.
Omer Charles A.
Ambrose Michael G.
Daniel Mark R.
Merck & Co. , Inc.
Muthard David A.
Richter Johann
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