Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus acids or salts thereof
Patent
1993-10-15
1996-05-21
Dees, Jose G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Phosphorus acids or salts thereof
C07F 938, A61K 3166
Patent
active
055191630
ABSTRACT:
Novel .alpha.-hydroxyphosphonate compounds which inhibit mammalian phosphoinositide-specific phospholipase-C. The compounds are potent anti-inflammatory and analgesic agents and may be useful for the treatment of cancer.
REFERENCES:
CA 118:39033t (1992).
Gibbs Jackson B.
Koblan Kenneth S.
MacLeod Angus M.
Merchant Kevin J.
Daniel Mark R.
Dees Jos,e G.
Frazier Barbara S.
Merck & Co. , Inc.
Muthard David A.
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