Inhibitors of phosphodiesterase IV for x-ray imaging

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – X-ray contrast imaging agent

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424 93, 424 95, A61K 4904, A61B 5055

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active

060834838

ABSTRACT:
The invention relates to the use of inhibitors of phosphodiesterase IV for the modulation of the motility and peristalsis of the hollow organs of the urogenital and gastrointestinal tract.

REFERENCES:
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Taher et al., World J Urol 1997 Springer-Verlag 1997, vol. 15, pp. 32-35.
Hermann Tenor and Christian Schudt. Phosphodiesterase Inhibitors (1996) pp. 21-23; and 34.
Stief et al., Urol Int. (1995) vol. 55, pp 183-189.
Goodman and Gilman, The Pharm. Basis of Ther., (1975) 5th ed., p. 735.
Giembycz et al., Biochemical Pharmacology, (1991) vol. 42, No. 3, pp 663-677.
Nicholson et al., Trends in Pharmacological Sciences, (1991) vol. 12, No. 1, pp. 19-27.
Dorland's Illustrated Medical Dictionary, (1965) 24th ed., p. 952.
Takashi Morita et al., Tohoku J. Exp. Med., (1987) vol. 151, pp. 201-204.
R. M. Weiss et al., J. of Pharm. and Exp. Ther., (1988) vol. 247, No. 2, pp. 630-634.

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