Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-12-19
2006-12-19
Habte, Kahsay (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S237200, C514S252140, C514S269000, C544S123000, C544S295000, C544S333000
Reexamination Certificate
active
07151101
ABSTRACT:
The present invention relates to inhibitors of p38, a mammalian protein kinase involved in cell proliferation, cell death and response to extracellular stimuli. The invention relates to compounds having the formula:or pharmaceutically acceptable salts thereof, wherein R1, Q1, Q2, and X are as described in the specification. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment end prevention of various disorders.
REFERENCES:
patent: 272843 (1989-10-01), None
patent: WO 86/06068 (1986-10-01), None
patent: WO 97/09984 (1997-03-01), None
patent: WO 97/33883 (1997-09-01), None
patent: WO 97/35855 (1997-10-01), None
patent: WO 98/07425 (1998-02-01), None
patent: WO 98/27098 (1998-06-01), None
Bemis Guy
Cochran John
Salituro Francesco
Fish & Neave IP Group Ropes & Gray LLP
Habte Kahsay
Haley Jr. James F.
Roise David A.
Vertex Pharmaceuticals Incorporated
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