Inhibitors of metalloproteinases

Details Inhibitors of metalloproteinases Inhibitors of metalloproteinases

2005-07-12

2005-07-12

Berch, Mark L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S364000, C544S360000, C514S253110, C514S253130

Reexamination Certificate

active

06916817

ABSTRACT:
Arylpiperazines of Formula I useful as metalloproteinase inhibitors, especially as MMP13 inhibitors.

REFERENCES:
patent: 5817822 (1998-10-01), MacPherson et al.
patent: 198 02 350 (1998-07-01), None
patent: WO 99/02510 (1999-01-01), None
patent: WO 99/18074 (1999-04-01), None
patent: WO 99/38843 (1999-08-01), None
patent: WO 00/12478 (2000-03-01), None
Coussens et al. {SCIENCE, vol. 295, Mar. 29, 2002}.

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