Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1998-05-19
1999-07-27
Tsang, Cecilia J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
546309, 544159, 514706, C07C32100
Patent
active
059292784
ABSTRACT:
Disclosed are novel inhibitors of metalloproteases, in particular matrix metalloproteases. The disclosed inhibitors are mercaptoketone and mercaptoalcohol compounds which are useful in pharmaceutical compositions and methods for treating or controlling disease states or conditions which involve tissue breakdown, for example, arthropathy, dermatological conditions, bone resorption, inflammatory diseases, and tumor invasion and in the promotion of wound healing.
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Campbell David A.
Patel Dinesh V.
Xiao Xiao-Yi
Affymax Technologies N.V.
Delacroix-Muirheid C.
Stevens Lauren L.
Swiss Gerald F.
Tsang Cecilia J.
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