Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.
Patent
1995-10-27
1998-11-03
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Tripeptides, e.g., tripeptide thyroliberin , etc.
514 18, 514 19, 564154, 546309, 544159, C07K 500
Patent
active
058310045
ABSTRACT:
Disclosed are novel inhibitors of metalloproteases, in particular matrix metalloproteases. The disclosed inhibitors are mercaptoketone and mercaptoalcohol compounds which are useful in pharmaceutical compositions and methods for treating or controlling disease states or conditions which involve tissue breakdown, for example, arthropathy, dermatological conditions, bone resorption, inflammatory diseases, and tumor invasion and in the promotion of wound healing.
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Campbell David A.
Patel Dinesh V.
Xiao Xiao-Yi
Affymax Technologies N.V.
Delacroix-Muirheid C.
Stevens Lauren L.
Swiss Gerald F.
Tsang Cecilia J.
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