Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-06-21
2011-06-21
Anderson, Rebecca L (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C435S015000, C548S494000
Reexamination Certificate
active
07964629
ABSTRACT:
The present invention relates, in general, to isoprenylcysteine carboxyl methyltransferase (Icmt) and, in particular, to inhibitors of Icmt and to methods of disease treatment using same.
REFERENCES:
patent: 5578634 (1996-11-01), Bach et al.
Baron, R. and Casey, P. “Analysis of the kinetic mechanism of recombinant human isoprenylcysteine carboxylmethyltrasnferase (lcmt),” BMC Biochemistry (2004)5:19, pp. 1-12.
Winter-Vann, A. et al, A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells, PNAS (2005), vol. 102(12), pp. 4336-4341.
Baron Rudi A.
Casey Patrick J.
Winter-Vann Ann M.
Anderson Rebecca L
Duke Universtiy
Nixon & Vanderhye P.C.
Otton Alicia L
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