Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-11-24
2008-10-07
Qazi, Sabiha N. (Department: 1612)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S374000, C548S215000, C548S225000
Reexamination Certificate
active
07432290
ABSTRACT:
The present invention relates to compounds which inhibit IMPDH. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH-mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
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Badia Michael C.
Bethiel Randy S.
Ronkin Steven M.
Saunders Jeffrey O.
Stamos Dean
Miller Canfield
O'Brien Jonathan P.
Qazi Sabiha N.
Vertex Pharmaceuticals Incorporated
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