Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-03-14
1999-08-03
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514367, 514374, 514375, 514388, 514397, 548146, 548161, 548181, 548222, 548239, 5483061, 5483114, 5483121, 5483255, A61K 31425, A61K 3142, C07D41312, C07D41712
Patent
active
059326000
ABSTRACT:
The present invention relates to a novel class of compounds which are IMPDH inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
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Armistead David M.
Badia Michael C.
Bethiel Randy S.
Frank Catharine A.
Naegele Doug
Govindaswamy N.
Haley, Jr. James F.
Raymond Richard L.
Vertex Pharmaceuticals Incorporated
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